Active ingredientBaloxavirCat. No. P-B004-001CAS 1985605-59-1
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Impurity or related compound · Baloxavir family
Pharmaceutical analytical standardBaloxavir Impurity 14
Synonyms: (3R)-2-[(11R)-7,8-Difluoro-6,11-dihydrobenzo[c][1]benzothiepin-11-yl]-11-phenylmethoxy-5-oxa-1,2,8-triazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-9,12-dione
- Cat. No.
- P-B004-025
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C31H25F2N3O4S
- Molecular weight
- 573.61 g/mol
- Category
- Impurity or related compound
Family: Baloxavir
An influenza antiviral discovered in Japan, where it was approved in February 2018, followed by the United States in October of the same year: it is a prodrug, baloxavir marboxil, taken as a single oral dose.
Did you know?It blocks 'cap snatching': the virus cuts the starting cap off the cell's messenger RNAs and uses it to launch its own. Baloxavir inhibits the enzyme that acts as the scissors.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Baloxavir family
Active ingredientBaloxavirCat. No. P-B004-001CAS 1985605-59-1
Isotopically labelledBaloxavir Impurity 61-d5Cat. No. P-B004-002
Isotopically labelledBaloxavir Marboxil-d3Cat. No. P-B004-003
Isotopically labelledBaloxavir Marboxil-d5Cat. No. P-B004-004
Isotopically labelledBaloxavir-d3Cat. No. P-B004-005
Isotopically labelledBaloxavir-d5Cat. No. P-B004-006
NitrosamineN-Nitroso Baloxavir Impurity 1Cat. No. P-B004-007
ImpurityBaloxavir Impurity 1Cat. No. P-B004-008CAS 16874-34-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.