Active ingredientBetamethasoneCat. No. P-B064-001CAS 378-44-9
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Pharmacopoeial impurity · Betamethasone family
Pharmaceutical analytical standardBeclometasone Dipropionate EP Impurity H
Synonyms: Beclomethasone 17-Monopropionate, Beclomethasone dipropionate EP Impurity H
- Cat. No.
- P-B064-163
- CAS
- 5534-18-9
- Alternative CAS
- N/A
- Formula
- C25H33ClO6
- Molecular weight
- 464.98 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Betamethasone
A synthetic corticosteroid developed in the late 1950s, with an anti-inflammatory effect about 25 times that of cortisol. It is used in creams, eye drops, injections and tablets.
Did you know?It is almost a twin of dexamethasone: the two molecules differ only in the orientation of one methyl group.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Beclometasone17-PropionateBP 760
More products in the Betamethasone family
Active ingredientBetamethasoneCat. No. P-B064-001CAS 378-44-9
Active ingredientBetamethasone 11-PhosphateCat. No. P-B064-002
Active ingredientBetamethasone 17-acetateCat. No. P-B064-003CAS 5534-12-3
Active ingredientBetamethasone 21-MesylateCat. No. P-B064-004CAS 1881-66-9
Active ingredientBetamethasone AcetateCat. No. P-B064-005CAS 987-24-6
Active ingredientBetamethasone DipropionateCat. No. P-B064-006CAS 5593-20-4
Active ingredientBetamethasone Sodium PhosphateCat. No. P-B064-007CAS 151-73-5
Active ingredientBetamethasone ValerateCat. No. P-B064-008CAS 2152-44-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.