Active ingredientBenazeprilCat. No. P-B026-001CAS 86541-75-5
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Pharmacopoeial impurity · Benazepril family
Pharmaceutical analytical standardBenazepril EP Impurity A Hydrochloride
Synonyms: Benazepril USP Related Compound A, Benazepril hydrochloride, (R,R)-, Benazepril EP Impurity A, Benazepril Enantiomer HCl, Benazepril EP Impurity A HCl, Benazepril hydrochloride impurities, Benazepril hydrochloride impurity A
- Cat. No.
- P-B026-004
- CAS
- 215447-89-5
- Alternative CAS
- 131064-75-0 (free base)
- 88372-38-7 (alternative CAS, same compound)
- Formula
- C24H28N2O5·HCl
- Molecular weight
- 460.95 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Benazepril
An ACE inhibitor that the body converts into the active metabolite benazeprilat, used for high blood pressure and heart failure; patented in 1981, it has been in use since 1990.
Did you know?It is also used in veterinary medicine: in dogs with heart failure and in cats and dogs with chronic kidney disease.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Benazepril family
Active ingredientBenazeprilCat. No. P-B026-001CAS 86541-75-5
Active ingredientBenazepril HClCat. No. P-B026-002CAS 86541-74-4
Pharmacopoeial impurityent-BenazeprilCat. No. P-B026-003CAS 131064-75-0
Pharmacopoeial impurityBenazepril EP Impurity B (1R,3S-Isomer)Cat. No. P-B026-005CAS 86541-76-6
Pharmacopoeial impurityBenazepril EP Impurity B HydrochlorideCat. No. P-B026-006CAS 86541-77-7
Pharmacopoeial impurityBenazepril EP Impurity CCat. No. P-B026-007CAS 86541-78-8
Pharmacopoeial impurityBenazepril EP Impurity FCat. No. P-B026-008CAS 109010-60-8
Pharmacopoeial impurityBenazepril EP Impurity GCat. No. P-B026-009CAS 103129-58-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.