Impurity or related compound · Ziprasidone family
Pharmaceutical analytical standardBenzo[d]isothiazol-3(2H)-one
Synonyms: 1,2-Benzisothiazol-3(2H)-one, 1,2-benzothiazol-3-one, Benzisothiazolone, Benzisothiazolinone, Proxel PL, Benzisothiazolin-3-one, Oristar bit, Proxel, Acticide BIT, Nipacide BIT, Proxel AB, Proxel XL 2, Caswell No. 079A, Caswell No. 513A, Benzocil, Canguard BIT, Denicide BIT, Proxel BD, Proxel CF, Proxel TN, Proxel XL, Proxel BDN, Proxel GXL, Proxel Ultra 5, San-aibac AP, Proxel LV-S, Proxel Press Paste, Apizas AP-DS, Acticide BW 20, Bestcide 200K, Nipacide BIT 20, Parmetol B 70, Parmetol D 11, Proxel GXL(S), Proxel HL 2, Nuosept 485, Nuosept 491, Nuosept 495, Topcide 600, XBINX, Denicide BIT 20N, Nipacide BIT 10W, Preventol BIT 20D, Proxel BD 20, Proxel Press Paste D, Troysan 1050, Bioban BIT 20DPG, Canguard BIT 20DPG, Canguard Ultra BIT 20LE, EPA Pesticide Chemical Code 098901, Benzisothiazol-3(2H)-one, Benzisothiazol-3(2h)-one, 1,2-
- Cat. No.
- P-Z019-018
- CAS
- 2634-33-5
- Alternative CAS
- 111337-53-2 (lithium salt)
- 58249-25-5 (sodium salt)
- 40991-37-5 (alternative CAS, same compound)
- Formula
- C7H5NOS
- Molecular weight
- 151.18 g/mol
- Category
- Impurity or related compound
Family: Ziprasidone
An atypical antipsychotic first approved in Sweden in 1998 and in the United States in 2001: it is used for schizophrenia and for manic and mixed episodes of bipolar disorder.
Did you know?It was first synthesised in 1987 at a research centre in Groton, Connecticut; chemically it is a structural analogue of risperidone, with a benzisothiazole group linked to a piperazine ring.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
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More products in the Ziprasidone family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
