Active ingredientBestatinCat. No. P-B059-001CAS 58970-76-6
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Impurity or related compound · Bestatin family
Pharmaceutical analytical standardBestatin Impurity 10
Synonyms: (2S,3R)-2-[(2S,3R)-2-Hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoyl]oxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-4-phenylbutanoic acid
- Cat. No.
- P-B059-015
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C30H40N2O9
- Molecular weight
- 572.65 g/mol
- Category
- Impurity or related compound
Family: Bestatin
An inhibitor of several aminopeptidases produced by the bacterium Streptomyces olivoreticuli, described in 1976 by the group of Japanese microbiologist Hamao Umezawa; also known as ubenimex, it has been studied in acute myeloid leukaemia and lymphoedema.
Did you know?It does not block just one enzyme but a small family: several aminopeptidases, which clip amino acids off the end of proteins, and leukotriene A4 hydrolase, involved in inflammation.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Bestatin family
Active ingredientBestatinCat. No. P-B059-001CAS 58970-76-6
Isotopically labelledBestatin-d5Cat. No. P-B059-002
Isotopically labelledBestatin-d7 HClCat. No. P-B059-003
Impurity1H-BenzotriazoleCat. No. P-B059-004CAS 95-14-7
Impurity3-Amino-2-hydroxy-4-phenylbutanoic acidCat. No. P-B059-005CAS 59554-14-2
ImpurityBestatin Impurity 1 HydrochlorideCat. No. P-B059-006
ImpurityBestatin Impurity 2 HydrochlorideCat. No. P-B059-007
ImpurityBestatin Impurity 3 HydrochlorideCat. No. P-B059-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.