Active ingredientBrimonidineCat. No. P-B109-001CAS 59803-98-4
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Active ingredient · Brimonidine family
Pharmaceutical analytical standardBrimonidine Tartrate
Synonyms: Alphagan, Qoliana, Lumify, Bromoxidine tartrate, Brominide tartrate, Mirvaso, Brymont, LUMIFY Redness Reliever Eye Drops, Lumify preservative free eye drops, Alphagan P
- Cat. No.
- P-B109-002
- CAS
- 70359-46-5
- Alternative CAS
- 59803-98-4 (free base)
- 1400635-36-0 (tartrate)
- 79570-19-7 (alternative CAS, same compound)
- 109826-56-4 (alternative CAS, same compound)
- Formula
- C11H10BrN5·C4H6O6
- Molecular weight
- 442.23 g/mol
- Category
- Active ingredient (API)
Family: Brimonidine
An alpha-2 adrenergic agonist used as eye drops to lower eye pressure in open-angle glaucoma and ocular hypertension, approved in the United States in 1996.
Did you know?It found a second life in dermatology: in 2013 the FDA approved a brimonidine gel that narrows small skin vessels and reduces facial redness in rosacea.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Brimonidine TartrateBP 1307
- Brimonidine tartrate CRSEP Y0001658
More products in the Brimonidine family
Active ingredientBrimonidineCat. No. P-B109-001CAS 59803-98-4
Pharmacopoeial impurityBrimonidine EP Impurity BCat. No. P-B109-003CAS 50358-63-9
Pharmacopoeial impurityBrimonidine EP Impurity CCat. No. P-B109-004CAS 6298-37-9
Pharmacopoeial impurityBrimonidine EP Impurity DCat. No. P-B109-005CAS 842138-74-3
Pharmacopoeial impurityBrimonidine EP Impurity ECat. No. P-B109-006CAS 168329-48-4
Pharmacopoeial impurityBrimonidine EP Impurity FCat. No. P-B109-007CAS 151110-15-5
Pharmacopoeial impurityBrimonidine EP Impurity GCat. No. P-B109-008CAS 1216379-05-3
Pharmacopoeial impurityBrimonidine EP Impurity G HClCat. No. P-B109-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.