Active ingredientCabazitaxelCat. No. P-C001-001CAS 183133-96-2
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Active ingredient · Cabazitaxel family
Pharmaceutical analytical standardCabazitaxel Acetone
Synonyms: Cabazitaxel acetone solvate, Cabazitaxel acetonate
- Cat. No.
- P-C001-006
- CAS
- 1426815-65-7
- Alternative CAS
- 183133-96-2 (other form)
- 1613316-39-4 (hydrate)
- Formula
- C45H57NO14·C3H6O
- Molecular weight
- 894.02 g/mol
- Category
- Active ingredient (API)
Family: Cabazitaxel
A semi-synthetic taxane that stops cell division by stabilising microtubules; approved in the United States in 2010 for metastatic castration-resistant prostate cancer previously treated with docetaxel.
Did you know?It is made by semi-synthesis from 10-deacetylbaccatin III, extracted from yew needles: the same genus of trees (Taxus) from which paclitaxel was isolated.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Cabazitaxel acetone CRSEP Y0002398
- Cabazitaxel for peak identification CRSEP Y0002413
- Cabazitaxel for system suitability CRSEP Y0002441
More products in the Cabazitaxel family
Active ingredientCabazitaxelCat. No. P-C001-001CAS 183133-96-2
Isotopically labelledCabazitaxel-d9Cat. No. P-C001-002CAS 1383572-19-7
Impurity(2'S,3'R)-CabazitaxelCat. No. P-C001-003CAS 1714967-27-7
Impurity4-Deacetyl-4-Propionyl-CabazitaxelCat. No. P-C001-005
ImpurityCabazitaxel Impurity 1Cat. No. P-C001-007CAS 159262-93-8
Pharmacopoeial impurityCabazitaxel EP Impurity FP-ACat. No. P-C001-008CAS 183133-94-0
ImpurityCabazitaxel Impurity 3Cat. No. P-C001-009
ImpurityCabazitaxel Impurity 4Cat. No. P-C001-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.