Active ingredientCabotegravirCat. No. P-C003-001CAS 1051375-10-0
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Impurity or related compound · Cabotegravir family
Pharmaceutical analytical standardCabotegravir Impurity 22
- Cat. No.
- P-C003-032
- CAS
- 2883234-41-9
- Alternative CAS
- N/A
- Formula
- C19H19N3O5
- Molecular weight
- 369.38 g/mol
- Category
- Impurity or related compound
Family: Cabotegravir
An HIV integrase inhibitor, blocking the enzyme the virus uses to insert its genome into human DNA. It was approved in 2020 and 2021 for treatment, together with rilpivirine, and in 2021 in the United States for prevention as well.
Did you know?Injected into muscle it has a half-life of weeks, compared with about 41 hours for the tablets: with rilpivirine it was the first antiretroviral available as a long-acting injection.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Cabotegravir family
Active ingredientCabotegravirCat. No. P-C003-001CAS 1051375-10-0
MetaboliteCabotegravir GlucuronideCat. No. P-C003-002
MetaboliteCabotegravir Metabolite 1Cat. No. P-C003-003CAS 2170827-76-4
Isotopically labelledCabotegravir-d5Cat. No. P-C003-004CAS 2750534-77-9
NitrosamineN-Nitroso CabotegravirCat. No. P-C003-005
ImpurityCabotegravir Impurity 1Cat. No. P-C003-006CAS 2883234-42-0
ImpurityCabotegravir Impurity 2Cat. No. P-C003-008
ImpurityCabotegravir Impurity 3Cat. No. P-C003-009CAS 2757656-11-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.