Active ingredientCalcipotriolCat. No. P-C008-001CAS 112965-21-6
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Pharmacopoeial impurity · Calcipotriol family
Pharmaceutical analytical standardCalcipotriol EP Impurity D
Synonyms: Calcipotriol, 24R-, Calcipotriol impurity d (ep impurity), Calcipotriene impurity d (usp impurity), Calcipotriol Impurity D
- Cat. No.
- P-C008-006
- CAS
- 112827-99-3
- Alternative CAS
- N/A
- Formula
- C27H40O3
- Molecular weight
- 412.61 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Calcipotriol
A synthetic vitamin D analogue patented in 1985 and in use since 1991: applied to the skin as a cream or ointment, it slows the proliferation of keratinocytes in plaque psoriasis.
Did you know?It binds the vitamin D receptor almost as well as calcitriol, the natural hormone, but it is over a hundred times less active on calcium metabolism: this is why it can be used on the skin with less risk of upsetting it.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Calcipotriol family
Active ingredientCalcipotriolCat. No. P-C008-001CAS 112965-21-6
Active ingredientCalcipotriol MonohydrateCat. No. P-C008-002CAS 147657-22-5
Pharmacopoeial impurityCalcipotriol EP Impurity ACat. No. P-C008-003CAS 126860-83-1
Pharmacopoeial impurityCalcipotriol EP Impurity BCat. No. P-C008-004CAS 2948288-30-8
Pharmacopoeial impurityCalcipotriol EP Impurity CCat. No. P-C008-005CAS 113082-99-8
Pharmacopoeial impurityCalcipotriol EP Impurity ECat. No. P-C008-007CAS 112849-14-6
Pharmacopoeial impurityCalcipotriol EP Impurity FCat. No. P-C008-008CAS 112875-61-3
Pharmacopoeial impurityCalcipotriol EP Impurity GCat. No. P-C008-009Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.