Active ingredientCalcitoninCat. No. P-C009-001CAS 47931-85-1
Pharmacopoeial impurity · Calcitonin family
Pharmaceutical analytical standardCalcitonin EP Impurity F
Synonyms: Salmon, Calcitonin (Salmon) EP Impurity F
- Cat. No.
- P-C009-011
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C145H242N44O54S2
- Molecular weight
- 3529.90 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Calcitonin
A 32-amino-acid peptide hormone made by the C cells of the thyroid, which lowers blood calcium by restraining osteoclasts, the cells that resorb bone; it was discovered in the early 1960s by Harold Copp at the University of British Columbia, in Canada.
Did you know?In 1969 Copp himself helped isolate salmon calcitonin, which in humans is more potent and longer-lasting than the human hormone: that is why it is the form most used as a medicine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Calcitonin family
Active ingredientCalcitoninCat. No. P-C009-001CAS 47931-85-1
ImpurityCalcitonin Impurity 1Cat. No. P-C009-020
ImpurityCalcitonin Impurity 2Cat. No. P-C009-021
ImpurityCalcitonin Impurity 3Cat. No. P-C009-022
ImpurityCalcitonin Impurity 4Cat. No. P-C009-023
ImpurityCalcitonin Impurity 5Cat. No. P-C009-025
ImpurityCalcitonin Impurity 6Cat. No. P-C009-026
ImpurityCalcitonin Impurity 7Cat. No. P-C009-027Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.