Impurity or related compound · Alpha-Ketovaline family
Pharmaceutical analytical standardCalcium alpha-Ketovaline
Synonyms: Calcium 3-methyl-2-oxobutyrate, calcium bis(3-methyl-2-oxobutanoate), Butanoic acid, 3-methyl-2-oxo-, calcium salt, alpha-Ketoisovaleric acid calcium salt, Calcium alpha-ketoisovalerate, Calcium 3-methyl-2-oxobutanoate, alpha-ketovaline calcium salt, Bis(2-oxo-3-methylbutyric acid)calcium salt
- Cat. No.
- P-K001-005
- CAS
- 51828-94-5
- Alternative CAS
- 759-05-7 (free acid)
- 3715-29-5 (sodium salt)
- 1173023-03-4 (sodium salt)
- 353241-22-2 (hydrate)
- 15784-52-8 (potassium salt)
- Formula
- C10H14CaO6
- Molecular weight
- 270.29 g/mol
- Category
- Impurity or related compound
Family: Alpha-Ketovaline
The keto acid corresponding to valine (alpha-ketoisovaleric acid), a natural intermediate in the metabolism of this amino acid; as a calcium salt it is one of the keto analogues used with a low-protein diet in chronic kidney disease, where it is converted into valine.
Did you know?It is the precursor of pantothenic acid (vitamin B5) and readily loses CO2 to become isobutyraldehyde: a route used by engineered microorganisms to make the biofuel isobutanol.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
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Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
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