Pharmacopoeial impurityCandesartan Cilexetil EP Impurity ACat. No. P-C018-002CAS 139481-58-6
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Impurity or related compound · Candesartan family
Pharmaceutical analytical standardCandesartan Impurity 3
Synonyms: 2-Ethoxy-3-(tetrazolo[1,5-f]phenanthridin-6-ylmethyl)benzimidazole-4-carboxylic acid
- Cat. No.
- P-C018-028
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C24H18N6O3
- Molecular weight
- 438.45 g/mol
- Category
- Impurity or related compound
Family: Candesartan
A sartan patented in 1990 and approved in 1997 for hypertension and heart failure. It is taken as a prodrug, candesartan cilexetil, which enzymes in the intestinal wall convert into the active molecule during absorption.
Did you know?It is considered one of the most potent AT1 receptor blockers by weight, and researchers have also studied it for preventing migraine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
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Pharmacopoeial impurityCandesartan Cilexetil EP Impurity ICat. No. P-C018-009CAS 139481-69-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.