Active ingredientCarbidopaCat. No. P-C037-001CAS 38821-49-7
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Impurity or related compound · Carbidopa family
Pharmaceutical analytical standardCarbidopa Impurity 2 Hydrobromide
Synonyms: 3-Methylcinnoline-6,7-diol hydrobromide
- Cat. No.
- P-C037-027
- CAS
- N/A
- Alternative CAS
- 1176784-51-2 (free base)
- Formula
- C9H8N2O2·HBr
- Molecular weight
- 257.09 g/mol
- Category
- Impurity or related compound
Family: Carbidopa
A dopa decarboxylase inhibitor that does not enter the brain: combined with levodopa for Parkinson's disease, in a combination approved in the United States in 1975, it stops levodopa from turning into dopamine before it reaches the brain.
Did you know?It was born in the 1960s among analogues of methyldopa, a blood-pressure medicine; given with levodopa, it extends levodopa's half-life in the blood from about 50 minutes to an hour and a half.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Carbidopa family
Active ingredientCarbidopaCat. No. P-C037-001CAS 38821-49-7
Pharmacopoeial impurityCarbidopa EP Impurity B HydrochlorideCat. No. P-C037-002CAS 115054-62-1
Pharmacopoeial impurityCarbidopa EP Impurity BCat. No. P-C037-003CAS 18181-08-3
Pharmacopoeial impurityCarbidopa EP Impurity CCat. No. P-C037-004CAS 84488-77-7
Pharmacopoeial impurityCarbidopa EP Impurity C (as Racemate)Cat. No. P-C037-005CAS 85933-19-3
Pharmacopoeial impurityCarbidopa EP Impurity DCat. No. P-C037-006CAS 934371-48-9
Pharmacopoeial impurityCarbidopa EP Impurity ECat. No. P-C037-007CAS 52514-63-3
Pharmacopoeial impurityCarbidopa EP Impurity FCat. No. P-C037-008CAS 1458640-32-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.