Active ingredientCarbocisteineCat. No. P-C040-001CAS 638-23-3
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Impurity or related compound · Carbocisteine family
Pharmaceutical analytical standardCarbocisteine Impurity 14
Synonyms: (3R)-4-(Carboxymethyl)-5-oxothiomorpholine-3-carboxylic acid
- Cat. No.
- P-C040-023
- CAS
- 1601460-92-7
- Alternative CAS
- N/A
- Formula
- C7H9NO5S
- Molecular weight
- 219.21 g/mol
- Category
- Impurity or related compound
Family: Carbocisteine
A mucolytic derived from the amino acid cysteine, first described in 1951 and in medical use since 1960: it makes phlegm less thick and easier to cough up, for example in chronic obstructive pulmonary disease.
Did you know?It is made by attaching a carboxymethyl group to cysteine, using chloroacetic acid: hence its full name, S-carboxymethyl-L-cysteine, shortened to carbocisteine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Carbocisteine family
Active ingredientCarbocisteineCat. No. P-C040-001CAS 638-23-3
Isotopically labelledCarbocisteine-13C3Cat. No. P-C040-002CAS 1391068-19-1
ImpurityCarbocisteine SulfoxideCat. No. P-C040-003CAS 5439-87-2
Impurity2-((4-Oxoazetidin-2-yl)thio)acetic acidCat. No. P-C040-004CAS 31898-75-6
ImpurityCarbocisteine Impurity 1Cat. No. P-C040-005CAS 60115-66-4
Impurity3-(Carboxymethanesulfonyl)-L-alanineCat. No. P-C040-006CAS 25515-73-5
ImpurityCarbocisteine Impurity 2Cat. No. P-C040-007CAS 88620-38-6
ImpurityCarbocisteine Diethyl Ester HClCat. No. P-C040-008CAS 92282-33-2Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.