Active ingredientCarboxyamidotriazoleCat. No. P-C045-001CAS 99519-84-3
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Impurity or related compound · Carboxyamidotriazole family
Pharmaceutical analytical standardCarboxyamidotriazole Impurity 5
Synonyms: 5-[[3,5-Dichloro-4-(4-chlorobenzoyl)phenyl]methylamino]-2H-triazole-4-carboxamide
- Cat. No.
- P-C045-008
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C17H12Cl3N5O2
- Molecular weight
- 424.67 g/mol
- Category
- Impurity or related compound
Family: Carboxyamidotriazole
An inhibitor of calcium entry into cells through both voltage-gated and non-voltage-gated channels: studied in the United States since the 1990s as a cytostatic anticancer agent, able to slow tumour growth, invasiveness and the formation of new blood vessels. It has not been approved.
Did you know?In the chick embryo chorioallantoic membrane assay, a classic laboratory model for studying blood vessels, it blocks the formation of new capillaries.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Carboxyamidotriazole family
Active ingredientCarboxyamidotriazoleCat. No. P-C045-001CAS 99519-84-3
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Isotopically labelledCarboxyamidotriazole-d6Cat. No. P-C045-003
ImpurityCarboxyamidotriazole Impurity 1Cat. No. P-C045-004CAS 99508-25-5
ImpurityCarboxyamidotriazole Impurity 2Cat. No. P-C045-005CAS 99508-26-6
ImpurityCarboxyamidotriazole Impurity 3Cat. No. P-C045-006CAS 4342-08-9
ImpurityCarboxyamidotriazole Impurity 4Cat. No. P-C045-007CAS 203202-66-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.