Active ingredientCerdulatinibCat. No. P-C114-001CAS 1198300-79-6
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Stable isotope labelled · Cerdulatinib family
Pharmaceutical analytical standardCerdulatinib-d8
- Cat. No.
- P-C114-002
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C20H19D8N7O3S
- Molecular weight
- 453.59 g/mol
- Category
- Stable isotope labelled
Family: Cerdulatinib
An experimental oral dual-target inhibitor that blocks both the SYK kinase and the JAK kinases: it has been studied for blood cancers and in 2018 received US orphan drug designation for peripheral T-cell lymphoma.
Did you know?More than dual, it is almost a 'multi-tool': it hits as many as six different kinases with nanomolar potency, namely SYK, TYK2, JAK1, JAK2, JAK3 and FMS.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Cerdulatinib family
Active ingredientCerdulatinibCat. No. P-C114-001CAS 1198300-79-6
NitrosamineN-Nitroso CerdulatinibCat. No. P-C114-003
ImpurityCerdulatinib Impurity 1Cat. No. P-C114-004
ImpurityCerdulatinib Impurity 2Cat. No. P-C114-005
ImpurityVexicitinibCat. No. P-C114-006CAS 2230362-69-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.