Active ingredientCetirizineCat. No. P-C119-001CAS 83881-51-0
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Active ingredient · Cetirizine family
Pharmaceutical analytical standardCetirizine Dihydrochloride
Synonyms: Cetrine, Formistin, Alleroff, Zerviate, Zyrtec Allergy, Zyrtec Hives Relief, Children's Zyrtec Allergy, Quzyttir, Children's Zyrtec Hives Relief, Becoallergy, Cetiirizine, Pollenshield, Allacan, Allertek, Cetirocol, Piriteze, Ziralton, Cetec, Zynor, Childrens Zyrtec, Childrens Cetirzine, Aptrizine, Zyrtec, Alercet, Alerid, Alerlisin, Alergex, Alertisin, Cetriler, Cetzine, Ressital, Salvalerg, Setiral, Stopaler, Zyrzine, Riztec, Virdos, Zirtin, Cezin, Ryzen, Triz, Xero-sed, Cetalerg, Ceterifug, Cetirlan, Voltric, Zetir, OX-NLA, Acetic acid, (2-(4-((4-chlorophenyl)phenylmethyl)-1-piperazinyl)ethoxy)-, dihydrochloride, (+-)-
- Cat. No.
- P-C119-002
- CAS
- 83881-52-1
- Alternative CAS
- 83881-51-0 (free base)
- 798544-25-9 (hydrochloride)
- 83881-50-9 (potassium salt)
- Formula
- C21H25ClN2O3·2HCl
- Molecular weight
- 461.81 g/mol
- Category
- Active ingredient (API)
Family: Cetirizine
A second-generation H1 antihistamine, in medical use since 1987: it blocks the histamine behind sneezing, itching and watery eyes. It is used for allergic rhinitis and urticaria (hives).
Did you know?It is the main metabolite of hydroxyzine, an older antihistamine: anyone taking hydroxyzine effectively produces cetirizine in their own body.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Cetirizine HydrochlorideBP 837
- Cetirizine dihydrochloride CRSEP C0980650
- Cetirizine for peak identification CRSEP Y0001197
More products in the Cetirizine family
Active ingredientCetirizineCat. No. P-C119-001CAS 83881-51-0
Pharmacopoeial impurityCetirizine Dihydrochloride EP Impurity ACat. No. P-C119-003CAS 303-26-4
Pharmacopoeial impurityCetirizine Dihydrochloride EP Impurity BCat. No. P-C119-004CAS 1000690-91-4
Pharmacopoeial impurityCetirizine Dihydrochloride EP Impurity CCat. No. P-C119-005CAS 2702511-37-1
Pharmacopoeial impurityCetirizine Dihydrochloride EP Impurity DCat. No. P-C119-006CAS 346451-15-8
Pharmacopoeial impurityCetirizine Dihydrochloride EP Impurity ECat. No. P-C119-007CAS 83881-56-5
Pharmacopoeial impurityCetirizine Dihydrochloride EP Impurity FCat. No. P-C119-008CAS 83881-54-3
Pharmacopoeial impurityCetirizine EP Impurity BCat. No. P-C119-009CAS 113740-61-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.