Active ingredientChloramphenicolCat. No. P-C129-001CAS 56-75-7
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Pharmacopoeial impurity · Chloramphenicol family
Pharmaceutical analytical standardChloramphenicol EP Impurity B
Synonyms: 4-Nitrobenzaldehyde, p-Nitrobenzaldehyde, Benzaldehyde, 4-nitro-, p-Formylnitrobenzene, Benzaldehyde, p-nitro-, Para-nitrobenzaldehyde, NSC 6103, p-nitrobenzenealdehyde, Chloramphenicol Impurity B, Nitrobenzaldehyde, 4-
- Cat. No.
- P-C129-004
- CAS
- 555-16-8
- Alternative CAS
- N/A
- Formula
- C7H5NO3
- Molecular weight
- 151.12 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Chloramphenicol
A broad-spectrum antibiotic announced in 1947, made by Streptomyces venezuelae, a bacterium isolated from a soil sample collected near Caracas. It is used in eye drops and eye ointments and, systemically, only in some serious infections.
Did you know?It was the first antibiotic to be synthesised in the laboratory: the synthesis devised by chemist Mildred Rebstock made it possible to produce it in large quantities and cheaply, without relying on fermentation.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Chloramphenicol family
Active ingredientChloramphenicolCat. No. P-C129-001CAS 56-75-7
Active ingredientChloramphenicol Sodium SuccinateCat. No. P-C129-002CAS 982-57-0
Pharmacopoeial impurityChloramphenicol EP Impurity ACat. No. P-C129-003CAS 716-61-0
Isotopically labelledChloramphenicol-d4Cat. No. P-C129-005
Isotopically labelledChloramphenicol-D5Cat. No. P-C129-006CAS 202480-68-0
Isotopically labelledN-Nitroso Chloramphenicol-d4Cat. No. P-C129-007
NitrosamineN-Nitroso ChloramphenicolCat. No. P-C129-008
ImpurityChloramphenicol DipalmitateCat. No. P-C129-009CAS 17709-53-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.