Active ingredientChloroquine DihydrochlorideCat. No. P-C137-001CAS 3545-67-3
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Stable isotope labelled · Chloroquine family
Pharmaceutical analytical standardChloroquine-d5 Diphosphate
- Cat. No.
- P-C137-006
- CAS
- N/A
- Alternative CAS
- 3545-67-3 (unlabelled form, dihydrochloride)
- 50-63-5 (unlabelled form, phosphate)
- 6823-83-2 (unlabelled form, sulfate hydrate)
- Formula
- C18H21ClN3D5·2H3O4P
- Molecular weight
- 520.90 g/mol
- Category
- Stable isotope labelled
Family: Chloroquine
A 4-aminoquinoline antimalarial discovered in Germany in 1934: it is used to prevent and treat malaria, and beyond that also for lupus and rheumatoid arthritis.
Did you know?Its name reveals its kinship with quinine, extracted in the 1820s from the bark of the cinchona tree. Soon after its discovery it was set aside for about ten years, because it was thought too toxic.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Chloroquine family
Active ingredientChloroquine DihydrochlorideCat. No. P-C137-001CAS 3545-67-3
Active ingredientChloroquine PhosphateCat. No. P-C137-002CAS 50-63-5
Active ingredientChloroquine Sulfate MonohydrateCat. No. P-C137-003CAS 6823-83-2
Pharmacopoeial impurityChloroquine USP Related Compound E OxalateCat. No. P-C137-004
Pharmacopoeial impurityChloroquine USP Related Compound G SulfateCat. No. P-C137-005
Isotopically labelledDidesethyl Chloroquine-d4Cat. No. P-C137-008CAS 1215797-41-3
Isotopically labelledN-Acetyl Desethyl Chloroquine-d4Cat. No. P-C137-009CAS 1216619-20-3
Isotopically labelledN-Acetyl Desethyl Chloroquine-d5Cat. No. P-C137-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.