Active ingredientChlorpromazine HydrochlorideCat. No. P-C143-001CAS 69-09-0
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Pharmacopoeial impurity · Chlorpromazine family
Pharmaceutical analytical standardChlorpromazine EP Impurity D Hydrochloride
Synonyms: Chlorpromazine EP Impurity D HCI
- Cat. No.
- P-C143-005
- CAS
- 3953-65-9
- Alternative CAS
- 1225-64-5 (free base)
- Formula
- C16H17ClN2S·HCl
- Molecular weight
- 341.29 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Chlorpromazine
A phenothiazine synthesised in France in December 1950 by chemist Paul Charpentier and on the market since the early 1950s: it was the first antipsychotic drug and opened the era of modern psychopharmacology.
Did you know?It was born from the search for an antihistamine for surgery: French surgeon Henri Laborit noticed it made patients calm and detached and pushed for a trial in psychiatry, where Delay and Deniker confirmed the effect in Paris in 1952.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Chlorpromazine family
Active ingredientChlorpromazine HydrochlorideCat. No. P-C143-001CAS 69-09-0
Pharmacopoeial impurityChlorpromazine EP Impurity DCat. No. P-C143-002CAS 1225-64-5
Pharmacopoeial impurityChlorpromazine EP Impurity FCat. No. P-C143-003CAS 13094-24-1
Pharmacopoeial impurityChlorpromazine EP Impurity B DihydrochlorideCat. No. P-C143-004CAS 2512203-91-5
Pharmacopoeial impurityChlorpromazine EP Impurity F HydrochlorideCat. No. P-C143-006CAS 72372-62-4
Pharmacopoeial impurityChlorpromazine Hydrochloride EP Impurity ACat. No. P-C143-007CAS 969-99-3
Pharmacopoeial impurityChlorpromazine Hydrochloride EP Impurity ECat. No. P-C143-008CAS 92-39-7
Metabolite7-Hydroxy Chlorpromazine GlucuronideCat. No. P-C143-010CAS 15643-03-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.