Active ingredientCiclopirox OlamineCat. No. P-C157-002CAS 41621-49-2
Drag to rotate
Active ingredient · Ciclopirox family
Pharmaceutical analytical standardCiclopirox
Synonyms: 6-cyclohexyl-1-hydroxy-4-methylpyridin-2-one, Loprox, Penlac, Cyclopirox, Ciclodan, Dafnegin CSC, Terit, Loprox Gel, Graphene Nanoplatelets 5nm(thick), 170m2/g(surface area), 7micro m(diameter)
- Cat. No.
- P-C157-001
- CAS
- 29342-05-0
- Alternative CAS
- 41621-49-2 (olamine)
- Formula
- C12H17NO2
- Molecular weight
- 207.27 g/mol
- Category
- Active ingredient (API)
A broad-spectrum antifungal of the hydroxypyridone family, introduced in West Germany around 1980 for skin mycoses; in 1999 its nail lacquer was approved in the United States for onychomycosis.
Did you know?It does not work like the azoles: it binds trivalent metal ions such as iron and aluminium, depriving the enzymes the fungus uses to break down peroxides of the metal they need.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Ciclopirox CRSEP Y0000040
More products in the Ciclopirox family
Active ingredientCiclopirox OlamineCat. No. P-C157-002CAS 41621-49-2
Pharmacopoeial impurityCiclopirox Olamine EP Impurity ACat. No. P-C157-003CAS 1823487-53-1
Pharmacopoeial impurityCiclopirox Olamine EP Impurity BCat. No. P-C157-004CAS 14818-35-0
Pharmacopoeial impurityCiclopirox Olamine EP Impurity CCat. No. P-C157-005CAS 67587-24-0
MetaboliteCiclopirox GlucuronideCat. No. P-C157-006CAS 79419-54-8
MetaboliteCiclopirox Glucuronide Lithium SaltCat. No. P-C157-007
Isotopically labelledCiclopirox Glucuronide-d11 Lithium SaltCat. No. P-C157-008
Isotopically labelledCiclopirox-d11 GlucuronideCat. No. P-C157-009CAS 1279033-13-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.