Active ingredientCinchocaineCat. No. P-C167-001CAS 85-79-0
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Active ingredient · Cinchocaine family
Pharmaceutical analytical standardCinchocaine Hydrochloride
Synonyms: Dibucaine Hydrochloride, Dibucaine HCl, Percaine, Sovcainum, Percain, Sovcain, Percamin S, Cincaine hydrochloride, Cinchocainium chloride, Cinchokain hydrochlorid, Nupercaine hydrochloride, Benzolin (local anesthetic), Butoxycinchoninic acid diethylethylenediamide hydrochloride, Cinchoninamide, 2-butoxy-n-(2-(diethylamino)ethyl)-, monohydrochloride, Dibucaine hydrochloride (usp-rs), Dibucaine hydrochloride (usp monograph), Percamin, Cincaine chloride, Dibucaine hydrochloride (JP17/USP)
- Cat. No.
- P-C167-002
- CAS
- 61-12-1
- Alternative CAS
- 85-79-0 (free base)
- 7275-81-2 (benzoate)
- Formula
- C20H29N3O2·HCl
- Molecular weight
- 379.93 g/mol
- Category
- Active ingredient (API)
Family: Cinchocaine
An amide-type local anaesthetic derived from quinoline, in clinical use since around 1930: it is among the most potent and long-lasting of its class and is used in haemorrhoid creams and in spinal anaesthesia.
Did you know?It gives its name to the dibucaine number, a test devised in 1957 that measures how much it blocks blood cholinesterase, revealing people with an enzyme variant that clears some muscle relaxants slowly.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Cinchocaine hydrochloride CRSEP C2177000
More products in the Cinchocaine family
Active ingredientCinchocaineCat. No. P-C167-001CAS 85-79-0
Pharmacopoeial impurityCinchocaine EP Impurity ACat. No. P-C167-003CAS 87864-14-0
Pharmacopoeial impurityCinchocaine EP Impurity BCat. No. P-C167-004CAS 15733-89-8
Pharmacopoeial impurityCinchocaine EP Impurity CCat. No. P-C167-005CAS 87864-08-2
Pharmacopoeial impurityDibucaine Impurity DCat. No. P-C167-006CAS 10222-61-4
ImpurityCinchocaine Impurity 1Cat. No. P-C167-007CAS 51842-70-7
ImpurityCinchocaine Impurity 2Cat. No. P-C167-008CAS 84906-82-1
ImpurityCinchocaine N-OxideCat. No. P-C167-009CAS 87864-07-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.