Active ingredientClemastine FumarateCat. No. P-C186-001CAS 14976-57-9
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Pharmacopoeial impurity · Clemastine family
Pharmaceutical analytical standardClemastine EP Impurity A (Mixture of Diastereomers)
Synonyms: Clemastine N-Oxide, Clemastine EP Impurity A
- Cat. No.
- P-C186-002
- CAS
- 108825-05-4
- Alternative CAS
- N/A
- Formula
- C21H26ClNO2
- Molecular weight
- 359.89 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Clemastine
A first-generation sedating H1 antihistamine, patented in 1960 and in clinical use since 1967: it relieves hay fever, itching and hives.
Did you know?An old allergy medicine with a second life: at the University of California, San Francisco, it has been studied as a possible aid to repairing myelin in multiple sclerosis.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Clemastine family
Active ingredientClemastine FumarateCat. No. P-C186-001CAS 14976-57-9
Pharmacopoeial impurityClemastine EP Impurity A Fumarate (Mixture of Diastereomers)Cat. No. P-C186-003
Pharmacopoeial impurityClemastine EP Impurity BCat. No. P-C186-004CAS 1352549-49-5
Pharmacopoeial impurityClemastine EP Impurity DCat. No. P-C186-005CAS 67004-64-2
Pharmacopoeial impurityClemastine Fumarate EP Impurity CCat. No. P-C186-006CAS 59767-24-7
Pharmacopoeial impurityrac-Clemastine Fumarate EP Impurity B HClCat. No. P-C186-007
ImpurityClemastine Impurity 1Cat. No. P-C186-008CAS 20763-27-3
ImpurityClemastine Impurity 2 (R,S-isomer)Cat. No. P-C186-009CAS 61826-30-0Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.