Active ingredientClofibrateCat. No. P-C207-001CAS 637-07-0
Drag to rotate
Stable isotope labelled · Clofibrate family
Pharmaceutical analytical standardClofibrate-d4
Synonyms: ethyl 2-(4-chloro-2,3,5,6-tetradeuteriophenoxy)-2-methylpropanoate, Ethyl Clofibrate-d4 (4-chlorophenyl-d4)
- Cat. No.
- P-C207-002
- CAS
- 1189654-03-2
- Alternative CAS
- 637-07-0 (unlabelled form)
- Formula
- C12H11D4ClO3
- Molecular weight
- 246.72 g/mol
- Category
- Stable isotope labelled
Family: Clofibrate
One of the first fibrates, drugs that lower triglycerides and cholesterol: patented in 1958 and approved in 1963, it was long used for dyslipidaemia before being replaced by newer molecules.
Did you know?Its mechanism of action remained a mystery for decades: only in the 1990s was it discovered that fibrates activate the nuclear receptor PPAR-alpha, which regulates fat metabolism.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Clofibrate family
Active ingredientClofibrateCat. No. P-C207-001CAS 637-07-0
ImpurityClofibrate Methyl EsterCat. No. P-C207-003CAS 55162-41-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.