Active ingredientClomipramine HydrochlorideCat. No. P-C211-001CAS 17321-77-6
Drag to rotate
Pharmacopoeial impurity · Clomipramine family
Pharmaceutical analytical standardClomipramine EP Impurity F
Synonyms: 3-Chloroiminodibenzyl, 2-chloro-6,11-dihydro-5H-benzo[b][1]benzazepine, Clomipramine HCl EP Impurity F
- Cat. No.
- P-C211-007
- CAS
- 32943-25-2
- Alternative CAS
- N/A
- Formula
- C14H12ClN
- Molecular weight
- 229.71 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Clomipramine
A tricyclic antidepressant developed in Switzerland in the 1960s as a chlorinated derivative of imipramine, in use in Europe since 1970: the most potent of its class on serotonin reuptake, it is used for depression and obsessive-compulsive disorder.
Did you know?It reached the United States only in 1989, but as the first medicine approved specifically for obsessive-compulsive disorder.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Clomipramine Impurity FBP 983
- Clomipramine impurity F CRSEP Y0000134
More products in the Clomipramine family
Active ingredientClomipramine HydrochlorideCat. No. P-C211-001CAS 17321-77-6
Pharmacopoeial impurityClomipramine EP Impurity CCat. No. P-C211-002CAS 2095-42-3
Pharmacopoeial impurityDichlorimipramineCat. No. P-C211-003CAS 3589-22-8
Pharmacopoeial impurityClomipramine EP Impurity A DihydrochlorideCat. No. P-C211-004CAS 2305824-51-3
Pharmacopoeial impurityClomipramine EP Impurity C HydrochlorideCat. No. P-C211-005CAS 2724726-85-4
Pharmacopoeial impurityClomipramine EP Impurity D HydrochlorideCat. No. P-C211-006CAS 115189-28-1
Pharmacopoeial impurityClomipramine EP Impurity GCat. No. P-C211-008CAS 1425793-87-8
MetaboliteClomipramine N-GlucuronideCat. No. P-C211-010Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.