Active ingredientClosantel Sodium DihydrateCat. No. P-C225-002CAS 61438-64-0
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Active ingredient · Closantel family
Pharmaceutical analytical standardClosantel
Synonyms: Benzamide, N-(5-chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodo-, N-(5-Chloro-4-((4-chlorophenyl)cyanomethyl)-2-methylphenyl)-2-hydroxy-3,5-diiodobenzamide
- Cat. No.
- P-C225-001
- CAS
- 57808-65-8
- Alternative CAS
- 61438-64-0 (sodium salt)
- Formula
- C22H14Cl2I2N2O2
- Molecular weight
- 663.07 g/mol
- Category
- Active ingredient (API)
A veterinary antiparasitic of the salicylanilide family, studied since the 1970s and used in sheep and cattle mainly against liver fluke and against blood-feeding worms and arthropods.
Did you know?In the blood it stays more than 99% bound to plasma proteins and in sheep it lingers for over three weeks: this way it reaches exactly the blood-sucking parasites, such as Haemonchus contortus.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Closantel family
Active ingredientClosantel Sodium DihydrateCat. No. P-C225-002CAS 61438-64-0
Pharmacopoeial impurityClosantel EP Impurity ACat. No. P-C225-003CAS 133-91-5
Pharmacopoeial impurityClosantel EP Impurity BCat. No. P-C225-004CAS 61437-85-2
Pharmacopoeial impurityClosantel EP Impurity CCat. No. P-C225-005
Pharmacopoeial impurityClosantel EP Impurity FCat. No. P-C225-006CAS 50274-07-2
Pharmacopoeial impurityClosantel EP Impurity GCat. No. P-C225-007CAS 2724801-62-9
Pharmacopoeial impurityClosantel EP Impurity JCat. No. P-C225-008CAS 2731038-10-9
Isotopically labelledClosantel-(Benzoyl ring-13C6)Cat. No. P-C225-009CAS 1325559-20-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.