Active ingredientCloxacillinCat. No. P-C228-001CAS 61-72-3
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Active ingredient · Cloxacillin family
Pharmaceutical analytical standardCloxacillin Benzathine
Synonyms: Benzathine cloxacillin, Dry-Clox, Orbenin DC, Dry-Clox Intramammary Infusion, Cloxacillin, N,N'-dibenzylethylendiamin-salz
- Cat. No.
- P-C228-017
- CAS
- 23736-58-5
- Alternative CAS
- 642-78-4 (sodium salt)
- 7081-44-9 (sodium salt hydrate)
- Formula
- 2C19H18ClN3O5S·C16H20N2
- Molecular weight
- 1112.11 g/mol
- Category
- Active ingredient (API)
Family: Cloxacillin
A beta-lactamase-resistant semisynthetic penicillin, obtained in the early 1960s by modifying methicillin and approved in 1965 against infections caused by penicillinase-producing staphylococci.
Did you know?The prefix 'clo-' recalls the chlorine atom that sets it apart from oxacillin: the same family includes dicloxacillin, with two chlorine atoms, and flucloxacillin, with one chlorine and one fluorine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Cloxacillin BenzathineBP 088
More products in the Cloxacillin family
Active ingredientCloxacillinCat. No. P-C228-001CAS 61-72-3
Active ingredientCloxacillin Sodium MonohydrateCat. No. P-C228-002CAS 7081-44-9
Active ingredientCloxacillin Sodium SaltCat. No. P-C228-003CAS 642-78-4
Pharmacopoeial impurityCloxacillin EP Impurity ACat. No. P-C228-004CAS 1642629-96-6
Pharmacopoeial impurityCloxacillin EP Impurity B (Mixture of Diastereomers)Cat. No. P-C228-005CAS 1642559-64-5
Pharmacopoeial impurityCloxacillin EP Impurity DCat. No. P-C228-006CAS 23598-72-3
Pharmacopoeial impurityCloxacillin Sodium EP Impurity ECat. No. P-C228-007CAS 18704-55-7
Isotopically labelledCloxacillin-13C4 Sodium SaltCat. No. P-C228-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.