Active ingredientCortisoneCat. No. P-C250-001CAS 53-06-5
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Impurity or related compound · Cortisone family
Pharmaceutical analytical standardCortisone 17-Valerate
- Cat. No.
- P-C250-005
- CAS
- 136370-31-5
- Alternative CAS
- N/A
- Formula
- C26H36O6
- Molecular weight
- 444.57 g/mol
- Category
- Impurity or related compound
Family: Cortisone
A steroid hormone of the adrenal cortex, isolated in the 1930s in the United States by Edward Kendall and Harold Mason. It is a prodrug: the liver converts it into cortisol, the active form, and it has been used as an anti-inflammatory since the late 1940s.
Did you know?In Kendall's laboratory it was simply called “compound E” (cortisol was “compound F”); in Britain chemists worked out how to make it from hecogenin, extracted from the sisal plant.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Cortisone family
Active ingredientCortisoneCat. No. P-C250-001CAS 53-06-5
Active ingredientCortisone AcetateCat. No. P-C250-002CAS 50-04-4
Isotopically labelledCortisone-d5Cat. No. P-C250-003
ImpurityCortisone HemisuccinateCat. No. P-C250-004CAS 10215-75-5
ImpurityCortisone 21-ValerateCat. No. P-C250-006CAS 119698-10-1
ImpurityCortisone Succinate Sodium SaltCat. No. P-C250-007CAS 7415-42-1Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.