Isotopically labelledCotrimoxazole-13C-d3Cat. No. P-C251-002
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Active ingredient · Cotrimoxazole family
Pharmaceutical analytical standardCotrimoxazole
Synonyms: Trimforte, Gantrim, Sulfotrimin, Supracombin, Bactromin, Chemotrim, Duratrimet, Eltrianyl, Fectrim, Gantaprim, Helveprim, Laratrim, Linaris, Microtrim, Momentol, Septrim, Sigaprim, Sulfotrim, Tacumil, Teleprim, Thiocuran, Trigonyl, Trimesulf, Uroplus, Abacin, Baktar, Imexim, Suprim, Comox, Nopil, Omsat, Trimethoprim-sulfamethoxazole, Cotrim-Puren, Sulfamethoxazole Trimethoprim, Apo-Sulfatrim, Bactramin, Bactrimel, Uro-Septra, Trimosulfa, Abactrim, Trimethoprimsulfa, TMP-SMX, Trimethoprim-sulfamethoxazole combination, Biseptol, Oriprim, Kepinol Forte, Septra Grape, Septra Ds, Bactrim DS, Bactrim Pediatric, Uroplus DS, Uroplus SS, Sulfatrim Pediatric, Sulmeprim Pediatric, Bactoreduct, Cotrimhexal, Cotrimstada, Jenamoxazol, Trimetoger, Trimexazol, Agoprim, Alfatrim, Bacteral, Bactilen, Bactiver, Bactrizol, Bactropin, Berlocid, Bibacrim, Chemitrim, Cotribene, Cotriver, Dibaprim, Escoprim, Esteprim, Gantaprin, Groprim, Kemoprim, Maxtrim, Mikrosid, Oecotrim, Oxaprim, Pantoprim, Primazole, Servitrim, Sigaprin, Teleprin, Tribakin, Bacton, Ciplin, Bacterial forte, Microtrim forte, Duon, Trimetho comp, Cotrimox-Wolff, Bactrim Forte, Co-Trimaxazol, Cotrim Holsen, Cotrimoxazol AL, Strepto-Plus, Cotrim-Hefa, Trimexole-F, Baktrisid-DS, Co-trim-tablinen, Cotrim-radiopharm, Sulfa-Tyl, Sulfameth/TMP, Sulfameth/Trimeth, Cotrim Eu Rho, Cotrimoxazol-Cophar, Cotrim D.S., Cotrim.L.U.T., SMX-TMP, Sulfamethoxazole-trimeth, Sulfamethoxazole / TMP, Co-Trimazole, Bactrim, Septra, NSC 618652, Trimethoprim, Sulfamethoxazole Drug Combination
- Cat. No.
- P-C251-001
- CAS
- 8064-90-2
- Alternative CAS
- 738-70-5 (free base)
- 94232-28-7 (other salt)
- 50808-41-8 (alternative CAS, same compound)
- Formula
- C14H18N4O3·C10H11N3O3S
- Molecular weight
- 543.60 g/mol
- Category
- Active ingredient (API)
A combination of trimethoprim and sulfamethoxazole, which block two successive steps of folate synthesis in bacteria: born in the late 1960s, when their synergy was described, it is used against urinary and respiratory infections and Pneumocystis pneumonia.
Did you know?In the tablets the two active ingredients are in a 1:5 ratio, but in blood and tissues this becomes about 1:20: exactly the ratio that gives peak synergy.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Cotrimoxazole family
Isotopically labelledCotrimoxazole-13C-d3Cat. No. P-C251-002Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.