Pharmacopoeial impurityCyanocobalamin EP Impurity ACat. No. P-C261-002CAS 23208-66-4
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Active ingredient · Cyanocobalamin family
Pharmaceutical analytical standardCyanocobalamin
Synonyms: Vitamin B12, Coobalamed, Cynobal, Vatimin B12, Distivit (B12 peptide), Factor II (vitamin B12), Cobalamin (III), Vitamine B12, Anacobin
- Cat. No.
- P-C261-001
- CAS
- 68-19-9
- Alternative CAS
- N/A
- Formula
- C63H88CoN14O14P
- Molecular weight
- 1355.39 g/mol
- Category
- Active ingredient (API)
A synthetic, stable form of vitamin B12, essential for making red blood cells and for the nervous system; the vitamin was first isolated in 1948, from liver.
Did you know?At its centre sits a cobalt atom: it was the first biomolecule found to contain a carbon-metal bond. Its structure was revealed by X-ray crystallography by Dorothy Hodgkin, winner of the 1964 Nobel Prize in Chemistry.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- CyanocobalaminBP 466
- Cyanocobalamin CRSEP C3000000
- Cyanocobalamin for peak identification CRSEP Y0002203
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Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.