Active ingredientCyclizineCat. No. P-C263-001CAS 82-92-8
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Active ingredient · Cyclizine family
Pharmaceutical analytical standardCyclizine HCl
Synonyms: Valoid, Collox, Piperazine, 1-(diphenylmethyl)-4-methyl-, monohydrochloride, Valiod, Marzine, Reis-fit, N-Benzhydryl-N'-methylpiperazine monohydrochloride, Echnatol, Fortravel, Component of Diconal, N-Benzhydryl-N -methylpiperazine
- Cat. No.
- P-C263-002
- CAS
- 303-25-3
- Alternative CAS
- 82-92-8 (free base)
- 7380-29-2 (alternative CAS, same compound)
- Formula
- C18H22N2·HCl
- Molecular weight
- 302.85 g/mol
- Category
- Active ingredient (API)
Family: Cyclizine
An antihistamine of the piperazine family, with anticholinergic action, discovered in 1947 in the United States: it soon proved a potent, long-acting antiemetic, used against nausea and vomiting from motion sickness, vertigo and anaesthesia.
Did you know?NASA chose it as the space-sickness medicine for Apollo 11, the first crewed flight to land on the Moon, in 1969.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Cyclizine HydrochlorideBP 096
- Cyclizine hydrochloride CRSEP C3090000
More products in the Cyclizine family
Active ingredientCyclizineCat. No. P-C263-001CAS 82-92-8
Pharmacopoeial impurityDiphenylmethanolCat. No. P-C263-003CAS 91-01-0
Pharmacopoeial impurityCyclizine EP Impurity ACat. No. P-C263-004CAS 109-01-3Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.