Active ingredientCytarabineCat. No. P-C279-001CAS 147-94-4
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Pharmacopoeial impurity · Cytarabine family
Pharmaceutical analytical standardCytarabine EP Impurity A
Synonyms: Uracil Arabinoside, Spongouridine, Arabinofuranosyluracil, Ara-U, Arabinosyluracil, NSC 68928, Uracil, 1-beta-D-arabinofuranosyl-, Sponguridine, Arabinoside, Uracil, Uracil Arabinofuranoside, Arabinofuranoside, Uracil, Arauridine, Spongouridin, Uracil-beta-D-arabinofuranoside, Uridine arabinoside, Vidarabine Impurity 2
- Cat. No.
- P-C279-002
- CAS
- 3083-77-0
- Alternative CAS
- N/A
- Formula
- C9H12N2O6
- Molecular weight
- 244.20 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Cytarabine
A nucleoside analogue of cytidine (cytosine arabinoside, ara-C) that blocks DNA synthesis: first synthesised in 1959 at the University of California, Berkeley, and approved in the United States in 1969, it is a mainstay of treatment for acute leukaemias.
Did you know?It grew out of the study of two unusual nucleosides containing the sugar arabinose, isolated in the 1950s from the Caribbean sponge Tectitethya crypta.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Uracil arabinoside CRSEP U0100000
More products in the Cytarabine family
Active ingredientCytarabineCat. No. P-C279-001CAS 147-94-4
Pharmacopoeial impurityCytarabine EP Impurity FCat. No. P-C279-003CAS 32830-01-6
Pharmacopoeial impurityCytarabine EP Impurity GCat. No. P-C279-004CAS 2140-61-6
Pharmacopoeial impurityCytarabine EP Impurity ICat. No. P-C279-005CAS 6829-31-8
Isotopically labelledCytarabine-13C-15N2Cat. No. P-C279-007
Isotopically labelledCytarabine-13C3Cat. No. P-C279-008
ImpurityCytarabine Impurity 1Cat. No. P-C279-009CAS 14057-18-2
Impurity1-Alpha-L-RibofuranosylcytosineCat. No. P-C279-010CAS 179239-81-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.