Impurity or related compound · Histidine family
Pharmaceutical analytical standardD-Histidine
Synonyms: D-Histamine, Histidine, d-, H-D-His-OH, D-His, D-Hls-OH, D-a-Amino-ss-(4-imidazolyl)propionic acid
- Cat. No.
- P-H023-013
- CAS
- 351-50-8
- Alternative CAS
- 328526-86-9 (hydrochloride hydrate)
- 6341-24-8 (hydrochloride)
- Formula
- C6H9N3O2
- Molecular weight
- 155.16 g/mol
- Category
- Impurity or related compound
Family: Histidine
An essential amino acid, which the body cannot make and must obtain from the diet. Its imidazole ring makes it valuable in the active sites of many enzymes, and it is the precursor of histamine, a key player in allergic reactions.
Did you know?Albrecht Kossel isolated it in 1896 from a protein in sturgeon sperm; the name probably comes from the Greek histos, linked to the idea of tissue, like that of the histones he had named himself.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
Shipped under controlled temperature when the molecule requires it.
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Sent with every order.
Follow your shipment live, from our warehouse to your lab.
More products in the Histidine family
Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.
