Active ingredientDabigatranCat. No. P-D001-001CAS 211914-51-1
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Impurity or related compound · Dabigatran family
Pharmaceutical analytical standardDabigatran Impurity 8
Synonyms: 2-[(4-Carbamimidoylanilino)methyl]-1-methyl-N-[3-oxo-3-(pyridin-2-ylamino)propyl]-N-pyridin-2-ylbenzimidazole-5-carboxamide
- Cat. No.
- P-D001-059
- CAS
- 1422435-42-4
- Alternative CAS
- N/A
- Formula
- C30H29N9O2
- Molecular weight
- 547.62 g/mol
- Category
- Impurity or related compound
Family: Dabigatran
An oral anticoagulant that directly inhibits thrombin, approved in Europe in 2008. It is given as a prodrug, dabigatran etexilate, which the body converts into the active form.
Did you know?It was the first of the new oral anticoagulants to get a specific antidote, idarucizumab, an antibody that neutralises it within minutes.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dabigatran family
Active ingredientDabigatranCat. No. P-D001-001CAS 211914-51-1
Pharmacopoeial impurityDabigatran Etexilate EP Impurity B TosylateCat. No. P-D001-002CAS 872728-85-3
Pharmacopoeial impurityDabigatran Etexilate EP Impurity CCat. No. P-D001-003CAS 1610758-20-7
Pharmacopoeial impurityDabigatran Etexilate USP Related Compound ACat. No. P-D001-004CAS 1408238-40-3
MetaboliteDabigatran Acyl-beta-D-GlucuronideCat. No. P-D001-005CAS 1015167-40-4
MetaboliteDabigatran Acyl-O-2-D-Glucuronide Trifluoroacetic Acid SaltCat. No. P-D001-006
MetaboliteDabigatran Acyl-O-3-D-Glucuronide Trifluoroacetic Acid SaltCat. No. P-D001-007
MetaboliteDabigatran Acyl-O-4-D-Glucuronide Trifluoroacetic Acid SaltCat. No. P-D001-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.