Active ingredientDaprodustatCat. No. P-D017-001CAS 960539-70-2
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Impurity or related compound · Daprodustat family
Pharmaceutical analytical standardDaprodustat Impurity 13
Synonyms: 1,3-Dicyclohexyl-2,4,6-trioxo-1,3-diazinane-5-carboxylic acid, DCU Impurity 4
- Cat. No.
- P-D017-019
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C17H24N2O5
- Molecular weight
- 336.39 g/mol
- Category
- Impurity or related compound
Family: Daprodustat
An oral inhibitor of HIF prolyl hydroxylase that boosts the body's own production of erythropoietin: approved in Japan in 2020 and in the United States in 2023, it is used for anaemia of chronic kidney disease.
Did you know?It acts on the system cells use to sense oxygen, a discovery awarded the 2019 Nobel Prize in Medicine: in effect it makes the body believe it is at high altitude.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Daprodustat family
Active ingredientDaprodustatCat. No. P-D017-001CAS 960539-70-2
Isotopically labelledDaprodustat-d8Cat. No. P-D017-002CAS 2250290-94-7
ImpurityDaprodustat Impurity 1Cat. No. P-D017-003CAS 2883118-63-4
Impurity3-(Cyclohexylamino)-3-oxopropanoic acidCat. No. P-D017-004CAS 918641-99-3
ImpurityCyclohexyl isothiocyanateCat. No. P-D017-005CAS 1122-82-3
ImpurityDaprodustat Ethyl Ester ImpurityCat. No. P-D017-006CAS 960540-96-9
ImpurityDaprodustat Hydroxymethyl ImpurityCat. No. P-D017-007
ImpurityDaprodustat Impurity 2Cat. No. P-D017-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.