Active ingredientDarifenacinCat. No. P-D020-001CAS 133099-04-4
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Impurity or related compound · Darifenacin family
Pharmaceutical analytical standardDarifenacin Impurity 9
Synonyms: 2-[(3S)-1-[2-(2,3-Dihydro-1-benzofuran-5-yl)-2-oxoethyl]pyrrolidin-3-yl]-2,2-diphenylacetamide
- Cat. No.
- P-D020-024
- CAS
- 133034-07-8
- Alternative CAS
- 133034-08-9 (hydrochloride)
- Formula
- C28H28N2O3
- Molecular weight
- 440.54 g/mol
- Category
- Impurity or related compound
Family: Darifenacin
An antimuscarinic for overactive bladder, approved in 2004 in Europe and the United States: it relaxes the bladder muscle by blocking M3 muscarinic receptors, reducing urgency and frequency of urination.
Did you know?Of the five types of muscarinic receptor it clearly prefers M3, the one that makes the bladder contract: it binds it about 59 times more strongly than M2, the subtype that dominates in the heart.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Darifenacin family
Active ingredientDarifenacinCat. No. P-D020-001CAS 133099-04-4
Active ingredientDarifenacin HBrCat. No. P-D020-002CAS 133099-07-7
Isotopically labelledDarifenacin-d4Cat. No. P-D020-003CAS 1095598-84-7
Isotopically labelledDarifenacin-d4 HBrCat. No. P-D020-004
Isotopically labelledDarifenacin-d5Cat. No. P-D020-005
Isotopically labelledrac-Darifenacin-d4Cat. No. P-D020-006CAS 1189701-43-6
Impurity1-Tosyl-(3S)-hydroxy pyrrolidineCat. No. P-D020-007CAS 133034-00-1
ImpurityDarifenacin Impurity 1Cat. No. P-D020-008CAS 87776-76-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.