Active ingredientSilodosinCat. No. P-S042-001CAS 160970-54-7
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Impurity or related compound · Silodosin family
Pharmaceutical analytical standardDehydro Silodosin KSM-1 Tartrate
Synonyms: Dehydro Silodosin KSM-1 L-Tartrate
- Cat. No.
- P-S042-019
- CAS
- N/A
- Alternative CAS
- 1639265-45-4 (free base)
- Formula
- C22H23N3O2·C4H6O6
- Molecular weight
- 511.53 g/mol
- Category
- Impurity or related compound
Family: Silodosin
A highly selective alpha-blocker for the alpha-1A receptors of the prostate, bladder and urethra, approved in Japan in 2006 and in the United States in 2008 for urinary symptoms of benign prostatic hyperplasia.
Did you know?Its selectivity can be put in numbers: it binds alpha-1A receptors with an affinity more than 100 times higher than for other adrenergic receptors, and its glucuronide metabolite keeps about one eighth of that affinity.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Silodosin family
Active ingredientSilodosinCat. No. P-S042-001CAS 160970-54-7
MetaboliteSilodosin Glucuronide Lithium SaltCat. No. P-S042-002
MetaboliteSilodosin MetaboliteCat. No. P-S042-003CAS 1357252-79-9
MetaboliteSilodosin Metabolite Sodium SaltCat. No. P-S042-004CAS 2052161-52-9
MetaboliteSilodosin-D-GlucuronideCat. No. P-S042-005CAS 879396-70-0
MetaboliteSilodosin-D-Glucuronide DitrifluoroacetateCat. No. P-S042-006
MetaboliteSilodosin-D-Glucuronide Na SaltCat. No. P-S042-007CAS 879292-24-7
Isotopically labelledSilodosin Metabolite-d4Cat. No. P-S042-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.