Active ingredientDesidustatCat. No. P-D053-001CAS 1616690-16-4
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Impurity or related compound · Desidustat family
Pharmaceutical analytical standardDesidustat Impurity 1
Synonyms: N-(1-Benzyl-4-hydroxy-2-oxo-1,2-dihydroquinoline-3-carbonyl)glycine, 2-[(1-benzyl-4-hydroxy-2-oxoquinoline-3-carbonyl)amino]acetic acid, NSC 794199
- Cat. No.
- P-D053-004
- CAS
- 931398-72-0
- Alternative CAS
- 2377239-85-3 (sodium salt)
- 2288708-57-4 (sodium salt)
- Formula
- C19H16N2O5
- Molecular weight
- 352.35 g/mol
- Category
- Impurity or related compound
Family: Desidustat
An oral inhibitor of the prolyl hydroxylase (PHD) enzymes, studied in India and Australia: it boosts the body's own erythropoietin production against anaemia of chronic kidney disease, cleared in India between 2021 and 2022 and in China in 2026.
Did you know?It "tricks" the kidney by mimicking a lack of oxygen: it exploits the HIF factors, which cells use to adapt to the oxygen available, a mechanism explained by Kaelin, Ratcliffe and Semenza, awarded the 2019 Nobel Prize in Medicine.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Desidustat family
Active ingredientDesidustatCat. No. P-D053-001CAS 1616690-16-4
Isotopically labelledDesidustat Impurity 1-d7Cat. No. P-D053-002
Isotopically labelledDesidustat-d4Cat. No. P-D053-003Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.