Isotopically labelledTrichlorfon-d6Cat. No. P-M111-002CAS 1451910-96-5
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Impurity or related compound · Metrifonate family
Pharmaceutical analytical standardDesmethylmetrifonate
Synonyms: Desmethyl-trichlorfon, methoxy-(2,2,2-trichloro-1-hydroxyethyl)phosphinic acid, Demethyltrichlorphon, Demethyltrichlorfon, Phosphonic acid, (2,2,2-trichloro-1-hydroxyethyl)-, monomethyl ester, Methyl hydrogen (2,2,2-trichloro-1-hydroxyethyl)phosphonate, Monodesmethylmetrifonate, Methyl (RS)-(2,2,2-Trichloro-1-hydroxyethyl)phosphonate Acid (Desmethylmetrifonate), Desmethylmetrifonate CRS, Desmethyltrichlorphone, Monomethyltrichlorphon, o-methyl-2,2,2-trichloro-1-hydroxyethylphosphonate, Phosphonic acid, p-(2,2,2-trichloro-1-hydroxyethyl)-, monomethyl ester
- Cat. No.
- P-M111-003
- CAS
- 684-31-1
- Alternative CAS
- 55869-01-7 (sodium salt)
- Formula
- C3H6Cl3O4P
- Molecular weight
- 243.40 g/mol
- Category
- Impurity or related compound
Family: Metrifonate
An organophosphorus cholinesterase inhibitor, introduced in 1952 as an insecticide (trichlorfon) and from 1960 used as a medicine for urinary schistosomiasis caused by Schistosoma haematobium; it was later also studied for Alzheimer's disease.
Did you know?It is an unusual prodrug: it turns by itself, without any enzymes, into dichlorvos, the molecule that actually inhibits cholinesterase.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
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More products in the Metrifonate family
Isotopically labelledTrichlorfon-d6Cat. No. P-M111-002CAS 1451910-96-5
ImpurityTrichlorfonCat. No. P-M111-004CAS 52-68-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
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