Active ingredientDeucravacitinibCat. No. P-D066-001CAS 1609392-27-9
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Impurity or related compound · Deucravacitinib family
Pharmaceutical analytical standardDeucravacitinib Impurity 1
Synonyms: 2-Methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)aniline, 2-methoxy-3-(1-methyl-1,2,4-triazol-3-yl)aniline, Benzenamine, 2-methoxy-3-(1-methyl-1H-1,2,4-triazol-3-yl)-
- Cat. No.
- P-D066-010
- CAS
- 1609394-10-6
- Alternative CAS
- N/A
- Formula
- C10H12N4O
- Molecular weight
- 204.23 g/mol
- Category
- Impurity or related compound
Family: Deucravacitinib
The first TYK2 kinase inhibitor, taken by mouth, approved in the United States in 2022 for moderate to severe plaque psoriasis: it dampens the signals of inflammatory cytokines such as IL-23 and IL-12.
Did you know?The prefix 'deu-' recalls deuterium, the heavy hydrogen present in the molecule; moreover, it does not block the enzyme's active site but latches onto its regulatory domain.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Deucravacitinib family
Active ingredientDeucravacitinibCat. No. P-D066-001CAS 1609392-27-9
MetaboliteDeucravacitinib BMT-334616 MetaboliteCat. No. P-D066-002
MetaboliteDeucravacitinib M-11 MetaboliteCat. No. P-D066-003
Isotopically labelledDeucravacitinib D3Cat. No. P-D066-005CAS 1609393-89-6
Impurity2-Methoxy-3-nitrobenzamideCat. No. P-D066-011CAS 722538-98-9
ImpurityDeucravacitinib ImpurityCat. No. P-D066-012CAS 1609394-08-2
ImpurityDeucravacitinib Impurity 2Cat. No. P-D066-013CAS 2222717-56-6
ImpurityDeucravacitinib Impurity 3Cat. No. P-D066-014CAS 2245111-21-9Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.