Active ingredientDexamethasoneCat. No. P-D068-001CAS 50-02-2
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Active ingredient · Dexamethasone family
Pharmaceutical analytical standardDexamethasone-21-Formate
- Cat. No.
- P-D068-005
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C23H29FO6
- Molecular weight
- 420.48 g/mol
- Category
- Active ingredient (API)
Family: Dexamethasone
A synthetic glucocorticoid about 25 times more potent than cortisol, in use since 1958. Thanks to its strong anti-inflammatory and immunosuppressive action it is used in allergies, inflammatory and autoimmune diseases, and in cancer care.
Did you know?In June 2020 the RECOVERY trial, led by the University of Oxford, made it the first medicine shown to improve survival in patients hospitalised with severe COVID-19.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dexamethasone family
Active ingredientDexamethasoneCat. No. P-D068-001CAS 50-02-2
Active ingredientDexamethasone 21-PhosphateCat. No. P-D068-002CAS 312-93-6
Active ingredientDexamethasone AcetateCat. No. P-D068-003CAS 1177-87-3
Active ingredientDexamethasone Sodium PhosphateCat. No. P-D068-004CAS 2392-39-4
Pharmacopoeial impurityDexamethasone Acetate EP Impurity BCat. No. P-D068-007
Pharmacopoeial impurityDexamethasone Acetate EP Impurity CCat. No. P-D068-008
Pharmacopoeial impurityDexamethasone Acetate EP Impurity ECat. No. P-D068-009CAS 1524-94-3
Pharmacopoeial impurityDexamethasone Acetate EP Impurity FCat. No. P-D068-010CAS 2884-51-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.