Active ingredientDexchlorpheniramine MaleateCat. No. P-D070-001CAS 2438-32-6
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Impurity or related compound · Dexchlorpheniramine family
Pharmaceutical analytical standardDexchlorpheniramine N-Oxide
Synonyms: S-Chlorphenamine N-Oxide
- Cat. No.
- P-D070-004
- CAS
- 142494-46-0
- Alternative CAS
- N/A
- Formula
- C16H19ClN2O
- Molecular weight
- 290.79 g/mol
- Category
- Impurity or related compound
Family: Dexchlorpheniramine
A first-generation H1 antihistamine with anticholinergic activity: it is the dextrorotatory, pharmacologically active isomer of chlorphenamine, in medical use since 1959 against hay fever and urticaria.
Did you know?Chlorphenamine is a mixture of two mirror-image molecules, like right and left hands: at the human H1 receptor the "right-handed" form binds tens of times more tightly than the other, which adds little to the effect.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dexchlorpheniramine family
Active ingredientDexchlorpheniramine MaleateCat. No. P-D070-001CAS 2438-32-6
Pharmacopoeial impurityDexchlorpheniramine EP Impurity BCat. No. P-D070-002CAS 32188-09-3
NitrosamineN-Nitroso Desmethyl DexchlorpheniramineCat. No. P-D070-003
ImpurityDexchlorpheniramine Pyridine N-OxideCat. No. P-D070-005
Pharmacopoeial impurityDexchlorpheniramine EP Impurity B MaleateCat. No. P-D070-006CAS 23095-76-3
Pharmacopoeial impurityDexchlorpheniramine EP Impurity ACat. No. P-D070-007CAS 86-21-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.