Active ingredientDiflunisalCat. No. P-D114-001CAS 22494-42-4
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Impurity or related compound · Diflunisal family
Pharmaceutical analytical standardDiflunisal Isopropyl Ester
Synonyms: propan-2-yl 5-(2,4-difluorophenyl)-2-hydroxybenzoate, Isopropyl 2',4'-difluoro-4-hydroxybiphenyl-3-carboxylate
- Cat. No.
- P-D114-010
- CAS
- 1381777-24-7
- Alternative CAS
- N/A
- Formula
- C16H14F2O3
- Molecular weight
- 292.28 g/mol
- Category
- Impurity or related compound
Family: Diflunisal
A non-steroidal anti-inflammatory drug derived from salicylic acid, with two fluorine atoms, developed in 1971 in a search for more potent analogues of acetylsalicylic acid; it is used for pain, osteoarthritis and rheumatoid arthritis.
Did you know?Decades later it was found to stabilise transthyretin, a blood protein: in 2025 the European Union authorised it for hereditary transthyretin amyloidosis with polyneuropathy.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Diflunisal family
Active ingredientDiflunisalCat. No. P-D114-001CAS 22494-42-4
Active ingredientDiflunisal SulphateCat. No. P-D114-002CAS 101072-47-3
MetaboliteDiflunisal Acyl GlucuronideCat. No. P-D114-003CAS 58446-30-3
Isotopically labelledDiflunisal-d3Cat. No. P-D114-005CAS 1286107-99-0
ImpurityDiflunisal Impurity 1Cat. No. P-D114-006CAS 705564-12-1
ImpurityDiflunisal Impurity 2Cat. No. P-D114-007CAS 1258635-47-0
ImpurityDiflunisal Impurity 3Cat. No. P-D114-008CAS 1639462-15-9
ImpurityDiflunisal Ethyl EsterCat. No. P-D114-009CAS 126093-86-5Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.