Pharmacopoeial impurityDiltiazem EP Impurity A HydrochlorideCat. No. P-D126-002CAS 103532-27-0
Drag to rotate
Active ingredient · Diltiazem family
Pharmaceutical analytical standardDiltiazem Hydrochloride
Synonyms: Dilzene, Adizem, Dilzem, Masdil, Altiazem, Deltazen, Diladel, Dilpral, Dilrene, Tildiem, Cardizem LA, Britiazim, Zilden, Cardizem CD, Dilacor, Diltzac, Cardizem SR, Cartia XT, Taztia XT, Viazem XL, Cartia, TAZTIA, Tiazac extended release, Slozem, Calazem, Kentiazem, Tiamex, Optil, Calcicard cr, Dilcardia sr, Dilcardia xl, Disogram sr, Adizem-sr, Adizem-xl, Kenzem sr, Zildil sr, Bi-carzem sr, Bi-carzem xl, Matzim LA, Tiadylt er, Dilacor xr, Cardizem, Tiazac, Mono-Tildiem, Diltiasyn, Farmabes, Gadoserin, Miocardie, Presoken, Bruzem, Diltan, Lacerol, Myonil, Tiadil, Cardizem Retard, Dinisor Retard, Bi-Tildiem, Cardil, Dilren, Dilt-cd, Dilzicardin, Anginyl, Angitil, Angizem, Calcicard, Calnurs, Cardiazem, Cirilen, Citizen, Clarute, Corazet, Dilatam, Dilatame, Dilcard, Dilgard, Dilicardin, Diltahexal, Diltelan, Diltikor, Diltime, Dinisor, Dodexen, Entrydil, Helsibon, Incoril, Kaltiazen, Levozem, Longazem, Lytelsen, Metazem, Oxycardil, Pazeadin, Pentilzeno, Poltiazem, Tilazem, Trumsal, Ziruvate, Carzem, Diatal, Dilfar, Dilsal, Diltam, Doclis, Dyalac, Etizen, Etyzen, Herben, Kardil, Slozen, Tiaves, Ubicor, Zildem, Carex, Coras, Dazil, Dilem, Dilso, Hesor, Tazem, Iski, Altiazem Retard, Cardil Retard, Dil-Sonaramia, Dilzem Retard, Myonil Retard, Tildiem Retard, Uni Masdil, Altiazem RR, Cirilen AP, Tildiem CR, Tildiem LA, Adizem-CD, Diltan SR, Dilzem RR, Viazem SR, Dolizem, Dilt-XR, Dodexen A.P., Presokin A. P., Milptin, Carzen, Apo-dilti, Cardizem XL, Tiazac XC
- Cat. No.
- P-D126-001
- CAS
- 33286-22-5
- Alternative CAS
- 42399-41-7 (free base)
- 75472-92-3 (free base)
- 144604-00-2 (malate)
- 139492-78-7 (maleate)
- 38411-61-9 (alternative CAS, same compound)
- Formula
- C22H26N2O4S·HCl
- Molecular weight
- 450.98 g/mol
- Category
- Active ingredient (API)
A calcium channel blocker of the benzothiazepine class, synthesised in Japan in the late 1960s and approved in the United States in 1982: it is used for angina, high blood pressure and some arrhythmias.
Did you know?Not just tablets: applied locally as a cream it widens blood vessels and helps anal fissures to heal, a use far removed from cardiology.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Diltiazem HydrochlorideBP 726
- Diltiazem for system suitability CRSEP Y0001141
- Diltiazem hydrochloride CRSEP D1980000
More products in the Diltiazem family
Pharmacopoeial impurityDiltiazem EP Impurity A HydrochlorideCat. No. P-D126-002CAS 103532-27-0
Pharmacopoeial impurityDiltiazem EP Impurity BCat. No. P-D126-003CAS 87447-47-0
Pharmacopoeial impurityDiltiazem EP Impurity C HClCat. No. P-D126-004CAS 1286126-67-7
Pharmacopoeial impurityDiltiazem EP Impurity D HClCat. No. P-D126-005CAS 130606-60-9
Pharmacopoeial impurityDiltiazem EP Impurity ECat. No. P-D126-006CAS 42399-49-5
Pharmacopoeial impurityDiltiazem EP Impurity FCat. No. P-D126-007CAS 42399-40-6
Pharmacopoeial impurityDiltiazem EP Impurity F HClCat. No. P-D126-008CAS 75472-91-2
Pharmacopoeial impurityent-Diltiazem EP Impurity ACat. No. P-D126-009CAS 111188-70-6Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.