Pharmacopoeial impurityDinoprostone EP Impurity CCat. No. P-D136-002CAS 36150-00-2
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Pharmacopoeial impurity · Dinoprostone family
Pharmaceutical analytical standardDinoprostone EP Impurity E
Synonyms: Alprostadil (Prostaglandin E1) Impurity 9, Prostaglandin B2, Dinoprostone EP Impurity E (Free Base)
- Cat. No.
- P-D136-005
- CAS
- 71431-28-2
- Alternative CAS
- 13367-85-6 (alternative CAS, same compound)
- Formula
- C20H30O4
- Molecular weight
- 334.46 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Dinoprostone
It is prostaglandin E2, a molecule our body also makes, used as a medicine mainly to ripen the cervix and induce labour. It has been approved in the United States since 1977 and is on the WHO List of Essential Medicines.
Did you know?Prostaglandins were discovered in 1935 in human seminal fluid; PGE2 itself was identified in 1962 by Swedish biochemist Sune Bergström in sheep seminal fluid.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dinoprostone family
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Pharmacopoeial impurityDinoprostone EP Impurity DCat. No. P-D136-004CAS 13345-50-1
Pharmacopoeial impurityDinoprostone EP Impurity FCat. No. P-D136-006CAS 26441-05-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.