Active ingredientDisopyramideCat. No. P-D153-001CAS 3737-09-5
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Active ingredient · Disopyramide family
Pharmaceutical analytical standardDisopyramide Phosphate
Synonyms: Norpace, Rythmodan, Norpace Cr, Dirythmin sa, Diso-duriles, NSC 756744, Dirythmin, Rythmodan ret, Isomide cr, Pharmakon1600-01500261, alpha-(2-Diisopropylaminoethyl)-alpha-phenyl-2-pyridineacetamide phosphate
- Cat. No.
- P-D153-002
- CAS
- 22059-60-5
- Alternative CAS
- 3737-09-5 (free base)
- 79190-73-1 (alternative CAS, same compound)
- Formula
- C21H29N3O·H3PO4
- Molecular weight
- 437.48 g/mol
- Category
- Active ingredient (API)
Family: Disopyramide
A class Ia antiarrhythmic that blocks sodium channels in heart cells, used since the 1970s for ventricular tachycardia and other arrhythmias.
Did you know?It also weakens the force of the heart's contraction: this is why it is used in obstructive hypertrophic cardiomyopathy, where it lowers the pressure difference that obstructs blood leaving the heart.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- Disopyramide phosphate CRSEP D2922000
More products in the Disopyramide family
Active ingredientDisopyramideCat. No. P-D153-001CAS 3737-09-5
Pharmacopoeial impurityDisopyramide EP Impurity DCat. No. P-D153-003CAS 5005-36-7
ImpurityDesisopropyl Disopyramide OxalateCat. No. P-D153-004CAS 88269-33-4
ImpurityDisopyramide EP Impurity A PhosphateCat. No. P-D153-005CAS 2724689-67-0
ImpurityDisopyramide EP Impurity B PhosphateCat. No. P-D153-006CAS 2731375-73-6
ImpurityDisopyramide N-Oxide DihydrochlorideCat. No. P-D153-007CAS 2731709-13-8Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.