Active ingredientDithranolCat. No. P-D157-001CAS 1143-38-0
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Pharmacopoeial impurity · Dithranol family
Pharmaceutical analytical standardDithranol EP Impurity B
Synonyms: 1,8-Dihydroxyanthraquinone, 1,8-dihydroxyanthracene-9,10-dione, Dantron, Chrysazin, Dorbane, Istizin, Antrapurol, Diaquone, Altan, Laxanorm, Laxanthreen, Laxipurin, Dionone, Zwitsalax, Danivac, Danthrone, Dantrone, Dioxyanthrachinonum, Usaf nd-59, Dantrona, Dantronum, LTAN, Anthraquinone, 1,8-dihydroxy-, Pilules Vinchy N.F., NSC 7210, NSC 38626, NSC 646568, Duolax, Laxipur, Chrysazine, Prugol, Roydan, Dorbanex, Criasazin, Istizine, Pastomin, Bancon, Istan, Component of Doxan, Neokutin S, Component of Modane, Scatron D, Component of Doxidan, Component of Dorbantyl, Anthraquinone,8-dihydroxy-, Laxapur, Danthron, BAN, Dantron, INN, Chrysazin, pract, Pharmakon1600-00211468, NSC 755828, Danthron (1,8-Dihydroxyanthracene-9,10-dione)
- Cat. No.
- P-D157-003
- CAS
- 117-10-2
- Alternative CAS
- 140861-59-2 (alternative CAS, same compound)
- Formula
- C14H8O4
- Molecular weight
- 240.21 g/mol
- Category
- Pharmacopoeial impurity (EP/USP)
Family: Dithranol
An anthracene derivative applied to the skin for psoriasis: it is the synthetic version of chrysarobin, the active principle of Goa powder, and its effect on psoriasis was discovered by Galewsky in 1916.
Did you know?Goa powder comes from the Brazilian tree Andira araroba: it is named after the Indian region of Goa, where it arrived around 1852.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
Pharmacopoeial standards available
The official European Pharmacopoeia standards for this molecule, supplied with EDQM documentation.
- DanthronBP 428
- Dantron Impurity StandardBP 429
More products in the Dithranol family
Active ingredientDithranolCat. No. P-D157-001CAS 1143-38-0
Pharmacopoeial impurityDithranol EP Impurity ACat. No. P-D157-002CAS 90-44-8
Pharmacopoeial impurityDithranol EP Impurity CCat. No. P-D157-004CAS 31991-54-5
Pharmacopoeial impurityDithranol EP Impurity DCat. No. P-D157-005CAS 1715-81-7Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.