Active ingredientDocetaxel AnhydrousCat. No. P-D161-001CAS 114977-28-5
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Impurity or related compound · Docetaxel family
Pharmaceutical analytical standardDocetaxel Impurity 29
Synonyms: [(1S,2S,3R,4S,5S,7S,8S,10R,13S)-5-Acetyloxy-1,4,7,10-tetrahydroxy-4-(hydroxymethyl)-13-[(2R,3S)-2-hydroxy-3-[(2-methylpropan-2-yl)oxycarbonylamino]-3-phenylpropanoyl]oxy-8,12,15,15-tetramethyl-9-oxo-2-tricyclo[9.3.1.03,8]pentadec-11-enyl] benzoate
- Cat. No.
- P-D161-059
- CAS
- 1385028-85-2
- Alternative CAS
- N/A
- Formula
- C43H55NO15
- Molecular weight
- 825.90 g/mol
- Category
- Impurity or related compound
Family: Docetaxel
A semi-synthetic taxane approved in the mid-1990s for breast, lung and prostate cancer. It is made from 10-deacetylbaccatin III, extracted from the needles of the European yew.
Did you know?Starting from the needles, which grow back, rather than the bark, production does not require cutting down the trees.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Docetaxel family
Active ingredientDocetaxel AnhydrousCat. No. P-D161-001CAS 114977-28-5
Active ingredientDocetaxel TrihydrateCat. No. P-D161-002CAS 148408-66-6
Pharmacopoeial impurityDocetaxel EP Impurity ACat. No. P-D161-003CAS 1887057-05-7
Pharmacopoeial impurityDocetaxel EP Impurity BCat. No. P-D161-004CAS 167074-97-7
Pharmacopoeial impurityDocetaxel EP Impurity DCat. No. P-D161-005CAS 162784-72-7
Pharmacopoeial impurityDocetaxel EP Impurity ECat. No. P-D161-006CAS 32981-86-5
Pharmacopoeial impurityDocetaxel EP Impurity GCat. No. P-D161-007CAS 125354-16-7
MetaboliteDocetaxel Metabolite 1Cat. No. P-D161-008Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.