Active ingredientDofetilideCat. No. P-D164-001CAS 115256-11-6
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Impurity or related compound · Dofetilide family
Pharmaceutical analytical standardDofetilide Impurity 5
Synonyms: N-[4-[2-[Methyl-[2-(4-nitrophenoxy)ethyl]amino]ethyl]phenyl]methanesulfonamide
- Cat. No.
- P-D164-009
- CAS
- N/A
- Alternative CAS
- N/A
- Formula
- C18H23N3O5S
- Molecular weight
- 393.46 g/mol
- Category
- Impurity or related compound
Family: Dofetilide
A class III antiarrhythmic that selectively blocks a potassium current in the heart (IKr), approved in 1999 in the United States and in Europe to restore and maintain normal rhythm in atrial fibrillation and flutter.
Did you know?In Europe it left the scene in 2004, when its authorisation was voluntarily withdrawn for commercial reasons, only five years after approval.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dofetilide family
Active ingredientDofetilideCat. No. P-D164-001CAS 115256-11-6
Isotopically labelledDofetilide-d4Cat. No. P-D164-002CAS 1189700-56-8
ImpurityDofetilide Impurity 1Cat. No. P-D164-004CAS 103790-20-1
ImpurityDofetilide Impurity 2Cat. No. P-D164-005CAS 56205-88-0
ImpurityDofetilide Impurity 3Cat. No. P-D164-007
ImpurityDofetilide Impurity 4Cat. No. P-D164-008
ImpurityDofetilide Impurity 6Cat. No. P-D164-010
ImpurityDofetilide Impurity 7Cat. No. P-D164-011Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.