Active ingredientDolutegravirCat. No. P-D166-001CAS 1051375-16-6
Drag to rotate
Impurity or related compound · Dolutegravir family
Pharmaceutical analytical standardDolutegravir Impurity 7
Synonyms: (3S,7R)-11-Hydroxy-7-methyl-9,12-dioxo-4-oxa-1,8-diazatricyclo[8.4.0.03,8]tetradeca-10,13-diene-13-carboxamide, Dolutegravir M1, Dolutegravir Amide
- Cat. No.
- P-D166-023
- CAS
- 1485081-26-2
- Alternative CAS
- N/A
- Formula
- C13H15N3O5
- Molecular weight
- 293.28 g/mol
- Category
- Impurity or related compound
Family: Dolutegravir
An antiretroviral integrase inhibitor, blocking the enzyme HIV uses to insert its genetic material into the host cell's DNA; approved in the United States in 2013 and in Europe in 2014.
Did you know?In 2019 the World Health Organization recommended it as both a first-line and a second-line treatment for all people living with HIV.
The two levels compared
| Level 1 Mass balance | Level 2 Mass balance + qNMR | |
|---|---|---|
| Identity (IR, MS, 1H and 13C-NMR; peptides: ESI-MS, MALDI-TOF and IR) | ✓ | ✓ |
| HPLC purity (min. 95%) | ✓ | ✓ |
| Content by mass balance (min. 90%; peptides: for information only)* | ✓ | ✓ |
| Content verified by qNMR (small molecules only) | · | ✓ |
| Suitable to qualify it as an in-house primary standard (ICH Q7) | · | ✓ |
* Mass balance is performed on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it, for example oils and highly volatile substances, on which some of the required measurements cannot be made: in those cases the CoA states how the content was assigned.
What you receive
The analytical standard
Shipped under controlled temperature when the molecule requires it.
Certificate of analysis (CoA)
For every lot: identity, purity and assay, with the supporting spectra and chromatograms.
Safety data sheet (SDS)
Sent with every order.
Tracked shipment
Follow your shipment live, from our warehouse to your lab.
More products in the Dolutegravir family
Active ingredientDolutegravirCat. No. P-D166-001CAS 1051375-16-6
Active ingredientDolutegravir SodiumCat. No. P-D166-002CAS 1051375-19-9
MetaboliteDolutegravir GlucuronideCat. No. P-D166-003
Isotopically labelledDolutegravir-d5Cat. No. P-D166-004CAS 2249814-82-0
Isotopically labelledDolutegravir-D6Cat. No. P-D166-005CAS 1407167-38-7
NitrosamineN-Nitroso Dolutegravir Impurity 1Cat. No. P-D166-006
Impurity4-Defluoro dolutegravirCat. No. P-D166-007CAS 1863916-87-3
Impurity4-Desfluoro-6-fluoro dolutegravirCat. No. P-D166-008CAS 2244161-72-4Frequently asked questions
Is mass balance always performed?
Yes, on every molecule. The only exceptions are cases where the chemistry of the molecule prevents it: for example oils and highly volatile substances, on which some measurements (such as thermogravimetry) cannot be made. In those cases the CoA states which method was used to assign the content.
Can I ask for a different quantity?
Yes. The quantities are only suggestions: choose "Other" and enter the milligrams or grams you need.
Which level should I choose?
Level 1 is enough for most routine testing. Level 2 adds an independent qNMR content value and is meant for labs that need to qualify an in-house primary standard. For peptides and similar molecules, Level 2 is not available.
When will I get the quote?
Within 24 working hours, with price, availability and delivery time.
Need a molecule you cannot find?
Custom synthesis of impurities, metabolites and labelled compounds, with the same characterisation level.